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Ischemic Stroke in Young Pts with Activated Protein C Resistance:Rpt of Three Cases Belonging to Three Different Kindreds Stroke 26:885-890, Simioni,P.,et al, 1995 See this aricle in Pubmed Article Abstract A new pathological condition termed"activated protein C(APC)resistance"has recently been reported to be the most common hereditary blood coagulation disorder associated with familial thrombosis.APC resistance is characterized by a poor anticoagulant response to APC in the plasma of patients and is due to a defect of factor V.This report deals with three Italian families with inherited APC resistance in which stroke had occurred at a young age in one of the family members.The cases reported here suggest a possible association of inherited APC resistance with ischemic stroke in young patients.Case-control studies should be performed to assess the true association.

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(click to filter results - removes previous filter) activated protein C resistance cerebrovascular accident cerebrovascular accident,familial occurrence cerebrovascular accident,young adult Factor V Leiden factor V,deficiency familial genetic neurologic disorders MRI MRI,abnormal thrombophlebitis

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